Clinical Flow Cytometry Platform
Navios
3 configurations
DxFLEX
7 configurations
Navios EX
3 configurations
Inheriting the classics and integrating innovation
Navios EX
• Powerful FSC detection capability-3 FSC detection angles
• 20bit high signal resolution, 40MHz sampling frequency
• Information amount that can be processed and stored per sample: 24 million cells/file
• Speed >50000 eps
• Flow cell and 32-tube automatic sampler
• Integrates CytoFLEX's excellent optical platform components
• Features an adjustable injection needle, sample dead volume 2ul, reducing sample loss
NAVIOS EX Fully Automated Flow Cytometer Specific Parameters
Parameters
• Solid-state lasers: 488nm, 55mW
638nm, 50mW
405nm, 80mW
• Software controlled laser switch
• Minimum fluorescence detection sensitivity:
FITC<28MESF;PE<30MESF;
APC<42MESF;PB<9MESF
• Fluorescence channel resolution <2%
• Three forward angle detection angles: N, W, W2
• Sample dead volume 2ul
• 32-tube continuous sampler, which can realize single-tube sampling and manual sampling in multiple modes
• Single-tube independent mixing
• Carryover rate <0.1%
• 20bit (1,048,576 channels) digital resolution; 40MHz sampling frequency
• 20L large flow cell, 89 tubes/hour
• Standard quality control provides L-J plot
• Remote diagnostic function
Equipment performance
• Flow cytometer host 3 lasers 10 colors B83535
• NaviosEX acquisition software Win7 version B91237
• NaviosEX workstation B80220
• Monitor
• UPS
Equipment performance
• Undertake routine clinical initial blood cancer patients' immune subtype analysis
• MRD monitoring of patients after treatment
• Immune monitoring after CarT therapy
• Undertake clinical new project development
Provide comprehensive flow cytometry reagent services
Antibodies and reagent kits
Monochromatic liquid reagents
Multicolor liquid combinations
Dry powder antibody solutions
Standardized reagent kits
Cytokine multiplex reagent kits
Up to 3 lasers with 13 colors
Flow cytometry cell preservation solution
Fluorescent microspheres and quality control products
Lysis, fixation permeabilization solution
Cell viability dyes
Sheath fluid cleaning solution, etc.
Reagent customization
CDS
CMS
Data analysis
Kaluza analysis software
Cytobank platform
Flow cytometry-specific cell preservation solution
FlowGuard® cell preservation solution
Medical device registration number: Zhe Wen Xie Bei 20160026
Used for sample preservation during flow cytometry experiments. It can protect samples at the initial stage of sampling (bone marrow, peripheral blood, cerebrospinal fluid, etc.), maintaining the stability of antigen expression.
Product features: Suitable for the detection of cell surface and intracellular CD molecules, providing diagnostic assurance for clinical immunotyping, lymphocyte subset detection, PNH detection, and other flow cytometry projects, ensuring accurate results; enabling multiple collections and single batch processing.
Does not affect FSC Durable and stable
| Item number | Model | Specifications | Feature | Scope of application |
| B160101-02 | FlowGuard®Flow cytometry specific cell preservation solution type I | 250ul/tube, 100 tubes/box | Type I cell preservation solution has a cell fixation effect and can preserve samples for up to 3 weeks. After preservation, the samples cannot be cultured, labeled with dead or alive dyes, or subjected to Ficoll separation of PBMCs | Peripheral blood, bone marrow, pleural effusion, ascites, cerebrospinal fluid, etc. |
| B160102-01 | FlowGuard®Flow cytometry specific cell preservation solution type I | 15ml/bottle | ||
| B160102-02 | FlowGuard®Flow cytometry specific cell preservation solution type I | 30ml/bottle | ||
| B160103-02 | FlowGuard®Flow cytometry specialized cell preservation solution type II | 250ul/tube, 100 tubes/box | Type II cell preservation solution contains special nutritional supplements that have no effect on the physical indicators and antigen expression of cells. It can continue to be cultured and can be labeled with dead or alive dyes | Peripheral blood, bone marrow, pleural effusion, ascites, cerebrospinal fluid, etc. |
| B160103-03 | FlowGuard®Flow cytometry specialized cell preservation solution type II | 15ml/bottle | ||
| B160103-04 | FlowGuard®Flow cytometry specialized cell preservation solution type II | 30ml/bottle | ||
| B160104-03 | FlowGuard®Flow cytometry specialized cell preservation solution type Ⅲ | 5ml/tube, 42 tube box | Type III cell preservation solution has a cell fixation effect and can preserve samples for up to 3 weeks. After preservation, samples cannot be cultured or labeled with dead or alive dyes | Organizational samples |
MagicFilter® MagicVajra® Kit (200 mesh)
Perfectly fits flow cytometry tubes, built-in 200/300 mesh nylon filter, designed with a convenient handle for easy fixation and operation. The inner wall of the filter is designed with patented special grinding teeth for efficient tissue grinding with minimal tissue damage. Coupled with cell preservation solution, it achieves extremely high cell yield and activity. It can be used for conventional filtration of bone marrow, peripheral blood, body fluids, and other specimens, as well as for easy grinding of solid tissues, making it a versatile tool.
The most commonly used methods for processing flow cytometry tissue specimens are enzymatic digestion and mechanical methods.
• Enzymatic digestion is time-consuming, and different tissues require different enzymes. Surface antigens are easily affected after digestion, so its application is limited. Therefore, most people still try to use mechanical methods.
• Many commercialized mechanical grinding machines are now available, such as those from BD and Miltenyi, but they are expensive.
Which is better, these grinding machines or manual methods?
The authors studied diseases such as diffuse large B-cell lymphoma, comparing 51 machine-ground, 27 manually-ground specimens, and 15 specimens combining machine and manual grinding of tissues.
Manual method: Tumor clone detection rate was 88.9%
Combination of machine and manual: Detection rate was 66.7%
Machine grinding: Only 62.7%
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